abstract：:In a randomized study, 42 patients undergoing extensive maxillo-facial surgery (correction of the position of the mandible or maxilla by using autologous bone transplants) received prophylactically ten-day courses of either flucloxacillin or amoxicillin with clavulanic acid. Patients were comparable with regard to age...

journal_title：Infection

authors： Vlaspolder F,de Zeeuw G,Rozenberg-Arska M,Egyedi P,Verhoef J

更新日期：1987-07-01 00:00:00

abstract：:The results of prenatal diagnosis of fetal rubella infection by specific IgM antibody detection in fetal infection by specific IgM antibody detection in fetal blood obtained in the 21st to 23rd weeks of pregnancy of women with different types of rubella problems during pregnancy (categorised in four groups) showed tha...

journal_title：Infection

authors： Enders G,Jonatha W

更新日期：1987-05-01 00:00:00

abstract：:After intravenous injection of single doses of 1.0 g of cefpirome (HR 810) and multiple doses of 1.0 g b.i.d. for five days to the same ten healthy male volunteers in an open design, concentrations of unchanged drug were estimated at various times in serum and urine, over 24 h and 48 h, respectively. Cefpirome concent...

journal_title：Infection

authors： Malerczyk V,Maass L,Verho M,Hajdú P,Klesel N,Rangoonwala R

更新日期：1987-05-01 00:00:00

abstract：:The aminoglycosides play a central role in the treatment of infectious diseases caused by gram-negative bacteria. During the period of January to June 1984, 45 clinical specimens collected in our neonatal intensive care unit grew Enterobacter cloacae; 41 of them were gentamicin resistant. One neonate developed septice...

journal_title：Infection

authors： Raz R,Sharir R,Shmilowitz L,Kenes I,Ephros M

更新日期：1987-01-01 00:00:00

abstract：:A guinea pig model of experimental Pseudomonas aeruginosa pneumonia was used to evaluate factors affecting the efficacy of passive immune therapy with Psomaglobin N, a hyperimmune P. aeruginosa globulin. Animals treated 2 h after infection with a single intravenous infusion of Psomaglobin N, 500 mg/kg, demonstrated 33...

journal_title：Infection

authors： Pennington JE,Pier GB

更新日期：1987-01-01 00:00:00

abstract：:A guinea pig model of experimental Pseudomonas aeruginosa pneumonia was used to evaluate factors affecting the efficacy of passive immune therapy with Psomaglobin N, a hyperimmune P. aeruginosa globulin. Animals treated 2 h after infection with a single intravenous infusion of Psomaglobin N, 500 mg/kg, demonstrated 33...

journal_title：Infection

authors： Pennington JE,Pier GB

更新日期：1987-01-01 00:00:00

abstract：:Twenty-four homosexual adult patients suffering from LAS or AIDS were investigated for immunoglobulin class- and IgG subclass-specific antibodies to human immunodeficiency virus (HIV) by the indirect ELISA and Western blot using monoclonal tracer antibodies. All patients revealed HIV-specific serum antibodies of IgG s...

journal_title：Infection

authors： Mergener K,Enzensberger W,Rübsamen-Waigmann H,von Briesen H,Doerr HW

更新日期：1987-01-01 00:00:00

abstract：:In a randomized controlled, clinical study the efficacy of ceftazidime at a dosage of 2 g b. i. d. was compared to that of cefotaxime at a dosage of 2 g t. i. d. or more in the treatment of pneumonia or peritonitis in intensive care patients. 61 of 67 assessable cases were evaluable. In the ceftazidime group ten out o...

journal_title：Infection

authors： Müller E,Heinkelein J

更新日期：1987-01-01 00:00:00

abstract：:The outer membrane proteins, F, H2 and I, from PA12 strain of Pseudomonas aeruginosa, were purified and used successfully for immunization of Balb/c mice. The immunized mice were protected against challenge with a 2-26 fold LD50 of all known 19 serogroups of P. aeruginosa. ...

journal_title：Infection

authors： von Specht BU,Strigl G,Ehret W,Brendel W

更新日期：1987-01-01 00:00:00

abstract：:A total of 208 patients underwent brain biopsy for presumptive herpes simplex encephalitis and were randomized to receive either vidarabine, vira-A, at 15 mg/kg/day, or acyclovir, at 30 mg/kg/day for ten days. 69 patients (33%) had biopsy-proven disease; 37 received vira-A and 32 acyclovir. With the exception of age, ...

journal_title：Infection

authors： Whitley RJ,Alford CA,Hirsch MS,Schooley RT,Luby JP,Aoki FY,Hanley D,Nahmias AJ,Soong SJ

更新日期：1987-01-01 00:00:00

abstract：:Zinc was found to have profoundly different effects upon the infection of McCoy cells (mouse fibroblasts) by two strains of Chlamydia trachomatis dependent upon the time and concentration of zinc exposure. Radiolabeled zinc-65 became McCoy cell-associated in a manner independent of incubation temperature, but highly d...

journal_title：Infection

authors： Sugarman B,Agbor P

更新日期：1987-01-01 00:00:00

abstract：:To assess the cost-effect relationship of aciclovir prophylaxis versus early treatment, we performed a retrospective study in 44 allogeneic bone marrow transplant recipients, who had only received aciclovir for therapeutic purposes. After bone marrow transplantation 18 herpes simplex infections occurred in 15 of the 3...

journal_title：Infection

authors： Sinnige LG,van der Meer JW,Gratama JW,Versteeg J,Zwaan FE

更新日期：1986-05-01 00:00:00

abstract：:Ten patients (mean age 63 years) undergoing alloarthroplastic hip joint replacement received 400 mg ofloxacin orally before anaesthesia. Venous blood samples were obtained before administration of the drug and then at intervals of up to 24 h. Bone samples were taken from femoral head and femoral shaft. Antibiotic conc...

journal_title：Infection

authors： Wittmann DH,Kotthaus E

更新日期：1986-01-01 00:00:00

abstract：:Imipenem/cilastatin in a doses of 1.5/day was used to treat 31 moderate to severe infections, predominantly soft tissue infections with bone involvement, in 30 surgical patients. A clinical success was achieved in 93% of the patients. In one patient with diabetic gangrene of the foot, imipenem/cilastatin treatment per...

journal_title：Infection

authors： Voeckl J,Fischer M

更新日期：1986-01-01 00:00:00

abstract：:Efficacy of Oral Ofloxacin and Ciprofloxacin. Cross-over Study. The efficacy of the 4-quinolones ciprofloxacin (CPX) and ofloxacin (OFX) was studied in a cross-over study. Twenty out-patients with cystic fibrosis and chronic colonization of the respiratory tract with Pseudomonas aeruginosa were treated for ten days wi...

journal_title：Infection

authors： Kurz CC,Marget W,Harms K,Bertele RM

更新日期：1986-01-01 00:00:00

abstract：:A time-dependent degree of immunosuppression or immunostimulation which may be correlated to pharmacokinetic variables was obtained by administering a single dose of ofloxacin, norfloxacin, pipemidic and piromidic acid to healthy volunteers. The plasma samples collected before drug administration and then at various t...

journal_title：Infection

authors： De Simone C,Vullo V,Grassi M,Di Fabio S,Baldinelli L,Sorice F

更新日期：1986-01-01 00:00:00

abstract：:The activity of ten different 4-quinolone antibacterial agents against Escherichia coli KL16 was investigated at four pH values between 5.6 and 8.3, which is the pH range of urine. It was found that pH affected the minimum inhibitory concentrations of all the drugs, but the nature of the substituent at the C7 position...

journal_title：Infection

authors： Smith JT,Ratcliffe NT

更新日期：1986-01-01 00:00:00

abstract：:The concentration of imipenem in organic bone, determined in 16 patients by bioassay after short infusion (15 min) of 1 g imipenem/cilastatin was 4.3 +/- 2.06 mg/kg (geometric mean +/- standard deviation, n = 13) after 45 minutes, and 2.8 +/- 1.86 mg/kg (n = 26) after 88 minutes. Imipenem penetrates into inorganic hyd...

journal_title：Infection

authors： Wittmann DH,Kuipers TH,Fock R,Höll M,Bauernfeind A

更新日期：1986-01-01 00:00:00

abstract：:Preliminary data from the U.S. regarding the safety and efficacy of ofloxacin in the treatment of urinary tract infections are presented. Treatment of uncomplicated urinary tract infections with either 200 mg or 300 mg ofloxacin b.i.d. was as effective as treatment with a standard therapy, co-trimoxazole. In another s...

journal_title：Infection

authors： Cox CE,Callery SV,Tack KJ

更新日期：1986-01-01 00:00:00

abstract：:We are presenting a new case of meningitis due to the Micrococcus luteus species. This germ was isolated twice in eight days from the CSF of a 57-year old woman. The patient had a ventriculoperitoneal shunt implanted for hydrocephalus following a meningeal haemorrhage. Antibiotic therapy was efficient but the patient ...

journal_title：Infection

authors： Fosse T,Peloux Y,Granthil C,Toga B,Bertrando J,Sethian M

更新日期：1985-11-01 00:00:00

abstract：:The incidence of urinary tract infections (UTI) in 299 renal graft transplantations (281 patients) was analyzed. UTI episodes were demonstrated in 185 grafts (62%), most frequently in the first month after transplantation. The infectious episodes were mostly recurrent. Persistent infection, detected in 11% of grafts, ...

journal_title：Infection

authors： Prát V,Horcicková M,Matousovic K,Hatala M,Liska M

更新日期：1985-09-01 00:00:00

abstract：:Minimal inhibitory concentrations (MIC) of enoxacin, nalidixic acid, pipemidic acid, norfloxacin, ciprofloxacin, ofloxacin and pefloxacin against isolates from 400 urological in-patients with complicated urinary tract infections (UTI) were determined by means of an agar dilution technique (10(4) cfu, multipointer). 28...

journal_title：Infection

authors： Naber KG,Sörgel F,Gutzler F,Bartosik-Wich B

更新日期：1985-09-01 00:00:00

abstract：:Aztreonam was given intravenously at a dose of 1 g at induction of anaesthesia, followed by subsequent doses of 1 g at eight hour intervals during 48 hours to 20 patients undergoing colorectal surgery. A series of serum and faecal specimens were taken for analysis of aztreonam concentrations. Tissue samples from the g...

journal_title：Infection

authors： Kager L,Brismar B,Malmborg AS,Nord CE

更新日期：1985-05-01 00:00:00

abstract：:There is a correlation between tissue oxygen tension, incidence of infection and disturbance of wound healing. Scientific investigations in recent years have documented that infection and tissue repair are processes consuming oxygen. Animal experiments have shown that oxygenation of the tissue is essential for the eli...

journal_title：Infection

authors： Kühne HH,Ullmann U,Kühne FW

更新日期：1985-03-01 00:00:00

abstract：:Cefotaxime is an effective antibiotic in lower respiratory tract infection caused by streptococci and staphylococci. There is a limited tendency to superinfections with Pseudomonas aeruginosa (1.5%) and there is a low incidence of side-effects. It is questionable whether there is really an urgent need for cefotaxime i...

journal_title：Infection

authors： Lode H,Glatzel PD

更新日期：1985-01-01 00:00:00

abstract：:Forty-six consecutive patients with pneumococcal meningitis were treated with cefotaxime (CTX). Ages ranged from 1-79 years: 29 adults, six adolescents, six children and five infants. Underlying diseases were found in 38 patients (82.6%). Twenty-six patients (56.5%) were admitted in coma. All isolates were sensitive t...

journal_title：Infection

authors： Lecour H,Seara A,Miranda AM,Cordeiro J

更新日期：1985-01-01 00:00:00

abstract：:The case of a 13-year-old girl with CVI is presented who required steroid treatment for myositis. After three weeks of treatment, the serum IgM level increased about ten-fold. Specific antibodies to vaccination antigens, which despite adequate vaccination were absent prior to any kind of treatment, could be synthesize...

journal_title：Infection

authors： Wahn V,Grosse-Wilde H,Rosin H,Carls C,Göbel U

更新日期：1985-01-01 00:00:00

abstract：:We studied the activity of cefotaxime both microbiologically and clinically. 138 blood cultures positive for gram-positive cocci were evaluated (90 strains of Staphylococcus aureus, 25 of Streptococcus faecalis, 13 of Streptococcus alpha and ten of Streptococcus mutans). Cefotaxime showed good activity against all str...

journal_title：Infection

authors： Bassetti D,Solbiati M,Fraizzoli G

更新日期：1985-01-01 00:00:00

abstract：:The purpose of this study was to determine the effectiveness and tolerability of norfloxacin, cinoxacin and oxolinic acid in the treatment of urinary tract infections (UTI) in comparison to nalidixic acid. 125 patients were given the drugs in the appropriate doses for 10-14 days and 30 patients were treated for six we...

journal_title：Infection

authors： Sabbour MS,El Bokl MA,Osman LM

更新日期：1984-11-01 00:00:00

abstract：:Thrombocytosis is rarely observed during infection. We are describing a patient with acute osteomyelitis and bacteremia who developed thrombocytosis. In the patient described the platelet count paralleled the activity of the infection and the response to therapy. The causes of thrombocytosis and its implications are b...

journal_title：Infection

authors： Robey C,Chmel H

更新日期：1984-11-01 00:00:00

abstract：:Penetration of ciprofloxacin into human tonsils was studied following an intravenous infusion of 200 mg over 15 minutes to adult humans undergoing tonsillectomy. Samples were taken one-and-a-half to four hours after dosing. Generally, tissue levels exceeded corresponding serum concentrations by 50% (range of intraindi...

journal_title：Infection

authors： Falser N,Dalhoff A,Weuta H

更新日期：1984-09-01 00:00:00

abstract：:The first case of Actinobacillus actinomycetem-comitans endocarditis in a child with a prosthetic cardiac valve is reported. Endocarditis was possibly caused by dental work done without antibiotic prophylaxis four weeks prior to admission. ...

journal_title：Infection

authors： Felius A,Fleer A,Moulaert A

更新日期：1984-07-01 00:00:00

abstract：:Clinical trials using interleukin 2 as a therapeutic immunomodulating agent in patients with acquired immunodeficiency syndrome have recently begun. In this article we present data from studies which indicate the ability of interleukin 2 in vitro to augment clinically important cytotoxic immune responses in lymphocyte...

journal_title：Infection

authors： Siegel JP,Rook AH,Djeu JY,Quinnan GV Jr

更新日期：1984-07-01 00:00:00

abstract：:Sera from 192 out-patient alcoholics attending a clinic for the treatment of alcoholism were tested for hepatitis B surface antigen (HBsAg) and for antibodies to HBsAg and to hepatitis B core antigen (HBcAg). Three sera (1.5%) were positive for HBsAg. Of the remaining 189 alcoholics, 29 (15%) were positive for one or ...

journal_title：Infection

authors： Gluud C,Gluud B,Aldershvile J,Jacobsen A,Dietrichson O

更新日期：1984-03-01 00:00:00

abstract：:Bacterial meningitis of infants and children exact a major toll worldwide. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis continue to be the major causes, and efforts to reduce the incidence of this disease have had limited success. Major advances in rapid diagnosis, such as antigen detect...

journal_title：Infection

authors： Marks MI

更新日期：1984-01-01 00:00:00

abstract：:The HBeAg/anti-HBe system was studied as a marker of infectivity and chronic progressive liver disease in 460 hemodialysis patients. The importance of HBeAg as an index of infectivity was confirmed in that it was present simultaneously with specific DNA polymerase (31 patients) and by the presence of widely diffuse co...

journal_title：Infection

authors： Fiaccadori F,David S,Faggion G,Feriani N,Ferrari C,Franco V,Giuberti T,Grutta D'Auria C,La Greca G,Magnani G

更新日期：1984-01-01 00:00:00

abstract：:The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

journal_title：Infection

authors： Husson MO,Courcol R,Izard D,Leclerc H

更新日期：1984-01-01 00:00:00

abstract：:Non-infected standardized burns and those contaminated experimentally with a constant number of organisms of a selected Pseudomonas aeruginosa strain underwent varying forms of treatment with silver sulfadiazine, cefsulodin cream and povidone iodine ointment. Wound healing was controlled by evaluating the wound area. ...

journal_title：Infection

authors： Kaiser W,von der Lieth H,Potel J,Heymann H

更新日期：1984-01-01 00:00:00

abstract：:We have reviewed 38 patients with brucellosis who were admitted to the Chaim Sheba Medical Center between 1955 and 1977, i.e. during a 23-year period. The clinical manifestations varied greatly. Diagnosis was easy when brucellosis was suspected, as in cases presenting with fever of unknown origin. In nine of the 38 ca...

journal_title：Infection

authors： Samra Y,Shaked Y,Hertz M,Altman G

更新日期：1983-11-01 00:00:00

abstract：:Combinations of amoxicillin and clavulanic acid were tested against 11 Escherichia coli strains and five Klebsiella aerogenes strains. Apart from one E. coli, the strains were highly resistant to amoxicillin due to beta-lactamase production. Synergy was demonstrated in all strains by agar dilution. Synergy was detecte...

journal_title：Infection

authors： Fuglesang JE,Bergan T

更新日期：1983-11-01 00:00:00